Original papers
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Pattern enrichment analysis for phage selection of stapled peptide ligands
T. Miki, K.Namii, K. Seko, S. Kakehi, G. Moro, H. Mihara
Chem. Sci. , 13, 12634-12642
Effects of Hydrophobic Residues on the Intracellular Self-Assembly of De Novo Designed Peptide Tags and Their Orthogonality
T. Miki, K. Kajiwara, S. Nakayama, M. Hashimoto, H. Mihara
ACS. Synth. Biol. , 11, 2144-2153
A guide-tag system controlling client enrichment into Y15 peptide-based granules for an in-cell protein recruitment assay
T. Miki, M. Hashimoto, T. Nakai. H. Mihara
Chem. Commun. , 57, 11338
Biofunctional supramolecular hydrogels fabricated from a short self-assembling peptide modified with bioactive sequences for the 3D culture of breast cancer MCF-7 cells
J. Y. Chia, T. Miki, H. Mihara, H. Tsutsumi
Bioorg. Med. Chem. , 46, 116345
Intracellular artificial supramolecules based on de novo designed Y15 peptides
T. Miki, T. Nakai, M. Hashimoto, K. Kajiwara, H. Tsutsumi, H. Mihara
Nat. Commun. , 12, 3412
(Editor's Highlight)
Selection of fluorescent biosensors against galectin-3 from an NBD-modified phage library displaying designed α-helical peptides
M. Hashimoto, T. Miki, I.Ven Chang, H. Tsutsumi, H. Mihara
Bioorg. Med. Chem. Lett., 37, 127835
Short self-assembling peptides with a urea bond: A new type of supramolecular peptide hydrogel materials
H. Tsutsumi, K. Tanaka, J.Yea Chia, H. Mihara
Biopolymers (Pept. Sci), 113(2), e24214
Construction of a Stapled α-Helix Peptide Library Displayed on Phage for the Screening of Galectin-3-Binding Peptide Ligands
T. Anananuchatkul, I.Ven Chang, T. Miki, H. Tsutsumi, H. Mihara
ACS Omega, 5(11), 5666-5674
hDM2 protein-binding peptides screened from stapled α-helical peptide phage display libraries with different types of staple linkers
T. Anananuchatkul, H. Tsutsumi, T. Miki, H. Mihara
Bioorg. Med. Chem., 30(23), 127605
Functionalization of self-assembling peptide materials using molecular recognition of supramolecular peptide nanofibers
H. Tsutsumi, D. Matsubara, H. Mihara
Polymer Journal., 52, 913-922
Self-Assembling Peptides as Building Blocks of Functional Materials for Biomedical Applications
K. Fukunaga, H. Tsutsumi, H. Mihara
Bull. Chem. Soc. Jpn., 92, 391-399
Gold Nanoparticles Conjugated with Glycopeptides for Lectin Detection and Imaging on Cell Surface
H. Tsutsumi, T. Shirai, H. Ohkusa, H. Mihara
Protein & Peptide Letters, 25(1), 84-89
Osteoblastic differentiation on hydrogels fabricated from Ca2+-responsive self-assembling peptides functionalized with bioactive peptides
H.Tsutsumi, M.Kawamura, H.Mihara
Bioorg. Med. Chem., 26(12), 3126-3132
Screening for concanavalin A binders from a mannose-modified α-helix peptide phage library
I.Ven Chang, H. Tsutsumi, H. Mihara
Mol. Biosyst., 13(11), 2222-2225
Cell Differentiation on Disk- and String-Shaped Hydrogels Fabricated from
Ca2+-responsive Self-Assembling Peptides
K. Fukunaga, H. Tsutsumi, H. Mihara
Biopolymers (Pept. Sci), 106, 476-483
Dihydrofolate Reductase Inhibitory Peptides Screened from a Structured Design β-Loop
Peptide Library Displayed on Phage
H. Tsutsumi, K. Nakano, H. Mihara
Mol. BioSyst., 11, 2713-2716
A Computational Study of the Interaction of Amphiphilic α-Helical
Cell-Penetrating Peptides with Heparan Sulfate
J. Yang, T. Furuta, M.Sakurai, H. Tsutsumi, H. Mihara
Bull. Chem. Soc. Jpn., 87, 1074-1082
Cellular Differentiation Assessments by Measuring the Degree of Cellular
Internalization and Membrane Adsorption Using Designed Peptides
K. Usui, T. Kikuchi, K. Kikuchi, M. Mie, E. Kobatake, H. Mihara
Bioorg. Med. Chem. Lett., 24, 4129-4131
Interaction of Amphiphilic α-Helical Cell-Penetrating Peptides with Heparan
Sulfate
J. Yang, H. Tsutsumi, T. Furuta, M. Sakurai, H. Mihara
Org. Biomol. Chem., 12, 4673-4681
Cell-Selective Intracellular Drug Delivery Using Doxorubicin and α-Helical
Peptides Conjugated to Gold Nanoparticles
H. Park, H. Tsutsumi, H. Mihara
Biomaterials., 35, 3480-3487.
Self-Assembling Peptide Nanofibers Promoting Cell Adhesion and Differentiation
K. Fukunaga, H. Tsutsumi, H. Mihara
Biopolymers., 100, 731-737.
Construction of Proteins with Molecular Recognition Capabilities Using α3β3 De Novo Protein Scaffolds
H. Okura, H. Mihara, T. Takahashi
Protein. Eng. Des. Sel., 26, 705-711.
A Monosaccharide-Modified Peptide Phage Library for Screening of Ligands
to Carbohydrate-Binding Proteins
K. Arai, H. Tsutsumi, H. Mihara
Bioorg. Med. Chem. Lett., 23, 4940-4943.
A Novel Array Format for Monitoring Cellular Uptake Using a Photo-Cleavable
Linker for Peptide Release
K. Usui, T. Kikuchi, KY. Tomizaki, T. Kakiyama, H. Mihara
Chem. Commun., 49, 6394-6396.
Cell Penetration and Cell-Selective Drug Delivery Using α-Helix Peptides
Conjugated with Gold Nanoparticles
H. Park, H. Tsutsumi, H. Mihara
Biomaterials., 34, 4872-4879.
Systematic Screening of the Cellular Uptake of Designed Alpha-Helix Peptides
K. Usui, T. Kikuchi, M. Mie, E. Kobatake, H. Mihara
Bioorg. Med. Chem., 21, 2560-2567.
Modification of a Small β-Barrel Protein, To Give Psudo-Amyloid Structures,
Inhibits Amyloid β-Peptide Aggregation
Y. Murakoshi, T. Takahashi, H. Mihara
Chem. Eur. J., 19, 4525-4531.
Gold Nanoparticles Conjugated with Monosaccharide-Modied Peptide for Lectin
Detection
H. Tsutsumi, H. Ohkusa, H. Park, T. Takahashi, H. Yuasa, H. Mihara
Bioorg. Med. Chem. Lett., 22, 6825-6827.
Noncompetitive On-Chip Immunoassays for Detection of Nonlabeled Antibodies Based on the Excluded Volume Effect of the Target Itself
K.-Y. Tomizaki, M. Obi, H. Mihara
Bull. Chem. Soc. Jpn., 85, 69-78.
Dense Surface Functionalization Using Peptides that Recognize Differences
in Organized Structures of Self-assembling Nanomaterials
T. Sawada, H. Mihara
Mol. BioSyst., 8, 1264-1274.
Cell-Adhesive Hydrogels Composed of Peptide NanofibersResponsive to Biological Ions
T. Sawada, M.Tsuchiya, T. Takahashi, H.Tsutsumi, H. Mihara
Polymer J., 44, 651-657.
Sensitive Detection of Small Molecule-Protein Interactions on a Metal-Insulator-Metal
Label-Free Biosensing Platform
A. Syahir, K. Kajikawa, H. Mihara
Chem. Asia. J., 7, 1867-1874.
Effects of Group 3 LEA Protein Model Peptides on Desiccation-induced Protein
Aggregation
T. Furuki, T. Shimizu, S. Chakrabortee, K. Yamakawa, R. Hatanaka, T. Takahashi, T. Kikawada, T. Okuda, H. Mihara, A. Tunnacliffe, M. Sakurai
BBA-proteins and proteomics, 1824, 891-897.
FRET Detection of Amyloid β-Peptide Oligomerization Using a Fluorescent Protein Probe Presenting a Pseudo-Amyloid Structure
T. Takahashi, H. Mihara
Chem. Commun., 48, 1568-1570.
Cell Fingerprint Patterns Using Designed α-Helical Peptides to Screen for
Cell-Specific Toxicity
K. Usui, T. Kakiyama, K. Tomizaki, M. Mie, E. Kobatake, H. Mihara
Bioorg. Med. Chem. Lett., 21, 6281-6284.
A Novel Peptide Array Using a Phage Display System for Protein Detection
T. Sawada, K. Ishiguro, T. Takahashi, H. Mihara
Chem. lett., 40, 508-509.
A Novel β-loop Scaffold of Phage-Displayed Peptides for Highly Specific
Affinities
T. Sawada, K. Ishiguro, T. Takahashi, H. Mihara
Mol. BioSyst., 7, 2558-2562.
"Selected as cover"
Rational Design of Amyloid β Peptide-Binding Proteins: Pseudo-Aβ β-Sheet Surface Presented in Green Fluorescent Protein Binds Tightly and Preferentially to Structured Aβ
T. Takahashi, K. Ohta, H. Mihara
Proteins., 78, 336-347.
Desiccation-Induced Structuralization and Glass Formation of Group 3 Late Embryogenesis Abundant Protein Model Peptides
T. Shimizu, Y. Kanamori, T. Furuki, T. Kikawada, T. Okuda, T. Takahashi, H. Mihara, M. Sakurai
Biochemistry, 49, 1093-1104.
A New Optical Label-Free Biosensing Platform Based on a Metal−Insulator−Metal Structure
A. Syahir, H. Mihara, K. Kajikawa
Langmuir, 26, 6053-6057.
Model Study of the Desiccation-induced Vitrification of Group-3 Late Embrogenesi Abundant Proteins
T. Furuki, T. Shimizu, T. Takahashi, H. Mihara, T. Kikawada, T. Okuda, M. Sakurai
Cryobiol. Cryotech., 56, 27-30.
Peptide Nanofibers Modified with a Protein by Using Designed Anchor Molecules Bearing Hydrophobic and Functional Moieties
A. Miyachi, T. Takahashi, S. Matsumura, H. Mihara
Chem. Eur. J., 16, 6644-6650.
Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with
Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12
M. Suzuki, T. Takahashi, J. Sato, M. Mie, E. Kobatake, H. Mihara
ChemBioChem, 11, 1525-1530.
Design and Conformational Analysis of Natively Folded β-Hairpin Peptides Stabilized by Nucleobase Interactions
R. Uozumi, T. Takahashi, T. Yamazaki, V. Granholm, H. Mihara
Biopolymers, 94, 830-842.
Affinity-Based Screening of Peptides Recognizing
Assembly States of Self-Assembling Peptide Nanomaterials
T. Sawada, T. Takahashi, H. Mihara
J. Am. Chem. Soc., 131, 14434-14441.
RNA Aptamers Selected Against Amyloid β-peptide (Aβ) Inhibit the Aggregation
of Aβ
T. Takahashi, K. Tada, H. Mihara
Mol. BioSyst., 5, 986-991.
Poly(amidoamine)-Dendrimer-Modified Gold Surfaces for Anomalous Reflection
of Gold To Detect Biomolecular Interactions
A. Syahir, K.-Y. Tomizaki, K. Kajikawa, H. Mihara
Langmuir, 25, 3667-3674.
Selection and Structural Analysis of De Novo Proteins from An α3β3 Genetic Library
M. T. Jumawid, T. Takahashi, T. Yamazaki, H. Ashigai, H. Mihara
Protein Sci., 18, 384-398.
Construction of Multi-functional Extracellular Matrix Protein that Increases
Number of N1E-115 Neuroblast Cells Having Neuritesa
M. Nakamura, M. Mie, H. Mihara, M. Nakamura, E. Kobatake
J. Biomed. Mater. Res. B Appl. Biomater., 91, 425-432.
Construction of Multi-Functional Extracellular Matrix Proteins that Promote
Tube Formation of Endothelial Cells
M. Nakamura, M. Mie, H. Mihara, M. Nakamura, E. Kobatake
Biomaterials, 29, 2977-2986.
Design of Peptides That Form Amyloid-Like Fibrils Capturing Amyloid β1-42
Peptides
J. Sato, T. Takahashi, H. Oshima, S. Matsumura, H. Mihara
Chem. Eur. J., 13, 7745-7752.
Embedding the Amyloid β-peptide Sequence in Green Fluorescent Protein Inhibits
Aβ Oligomerization
T. Takahashi, K. Ohta, H. Mihara
ChemBioChem, 8, 985-988.
"Selected as cover"
Phosphate-Mediated Molecular Memory Driven by Two Different Protein Kinases
as Information Input Elements
K.-Y. Tomizaki, H. Mihara
J. Am. Chem. Soc., 129, 8345-8352.
Interactions Between Peptides Containing Nucleobase Amino Acids and T7
Phages Displaying S. cerevisiae proteins
S. Watanabe, K.-Y. Tomizaki, T. Takahashi, K. Usui, K. Kajikawa, H. Mihara
Biopolymers, 88, 131-140.
Screening of α-helical Peptide Ligands Controlling a Calcineurin-phosphatase
Activity
K. Usui, K.-Y. Tomizaki, H. Mihara
Bioorg. Med. Chem. Lett., 17, 167-171.
Rational Design of Homogeneous Protein Kinase Assay Platforms that Allow
Both Fluorometric and Colorimetric Signal Readouts
K.-Y. Tomizaki, H. Mihara
Mol. BioSyst., 2, 580-589.
Protein-fingerprint Data Mining of a Designed α-helical Peptide Array
K. Usui, K.-Y. Tomizaki, H. Miara
Mol. BioSyst., 2, 417-420.
"Selected as cover"
Metal-triggered Nanofiber Formation of His-containing β-sheet Peptide
S. Matsumura, S. Uemura, H. Mihara
Suplamolc. Chem., 18, 397-403.
Utilization of L-α-nucleobase Amino Acids (NBAs) as Protein Engineering Tools: Construction of NBA-modified HIV-1 Protease Analogues and Enhancement of Dimerization Induced by Nucleobase Interaction
T. Takahashi, D. Yana, H. Mihara
ChemBioChem, 7, 729-732.
A Novel Peptide Microarray for Protein Detection and Analysis Utilizing
a Dry Peptide Array System
K. Usui, K.-Y. Tomizaki, T. Ohyama, K. Nokihara, H. Mihara
Mol. BioSyst., 2, 113-121.
A PNA-DNA Hybridization Chip Approach for the Detection of β-secretase
Activity
S. Sano, K.-Y. Tomizaki, K. Usui, H. Mihara
Bioorg. Med. Chem. Lett., 16, 503-506.
Binding Modes of the Precursor of Adenovirus Major Core Protein VII to
DNA and Template Activating Factor I: Implication for the Mechanism of
Remodeling of the Adenovirus Chromatin
B. Gyurcsik, H. Haruki, T. Takahashi, H. Mihara, K. Nagata
Biochemistry, 45, 303-313.
Nonfibrous β-structured Aggregation of an Aβ Model Peptide (Ad-2α) on GM1/DPPC
Mixed Monolayer Surfaces
T. Kawasaki, K. Asaoka, H. Mihara, Y. Okahata
J. Colloid Interface Sci., 294, 295-303.
A Chromism-Based Assay (CHROBA) Technique for in situ Detection of Protein Kinase Activity
K.-Y. Tomizaki, J. Xu, H. Mihara
Bioorg. Med. Chem. Lett., 15, 1731-1735.
IR Study on Stacking Manner of Peptide
Nanorings in Peptide Nanotubes
Y. Nagai, T. Nakanishi, H. Okamoto, K. Takeda, Y. Furukawa, K. Usui, H. Mihara
Jpn J. Appl. Phys., 44, 7654-7661.
Difference in Self-Assembling Morphology of Peptide Nanorings
H. Okamoto, T. Yamada, H. Miyazaki, T. Nakanishi, K. Takeda, K. Usui, I. Obataya, H. Mihara, H. Azehara, W.Mizutani, K. Hashimoto, H. Yamaguchi, Y.Hirayama
Jpn J. Appl. Phys., 44, 8240-8248.
Anomalous Reflection of Gold Applicable for
a Practical Protein-detecting Chip Platform
S. Watanabe, K. Usui, K.-Y. Tomizaki, K. Kajikawa, H. Mihara
Mol. BioSyst., 1, 363-365.
A Designed Glycopeptide Array for Characterization of Sugar-Binding Proteins Toward a Glycopeptide Chip Technology
K. Usui, T. Ojima, K.-Y. Tomizaki,, H. Mihara
NanoBiotechnology, 1, 191-200
Construction of biotinylated peptide nanotubes for arranging proteins
S. Matsumura, S. Uemura, H. Mihara
Mol. BioSyst., 1, 146-148.
A Novel Fluorescence Sensing System Using Photochromism-Based Assay (P-CHROBA)
Technique for Detection of Target Proteins
K. -Y. Tomizaki, H. Mihara
J. Mater. Chem., 15, 2732-2740.
Enantioselective ester hydrolysis catalyzed byβ-cyclodextrin conjugated with β-hairpin peptides
H. Tsutsumi, H. Ikeda, H. Mihara, A. Ueno
Bioorg. Med. Chem. Lett., 14, 723-726.
Construction of a chemically and conformationally self-replicating system
of amyloid-like fibrils
Y. Takahashi, H. Mihara
Bioorg. Med. Chem., 12, 693-699.
A Peptide-Cyclodextrin Hybrid System Capable of Detecting Guest Molecules
Utilizing Fluorescence Resonance Energy Transfer
D. Yana, T. Takahashi, H. Mihara, A. Ueno
Macromol. Rapid Commun., 25, 577-581.
Peptide Arrays with Designed Secondary Structure for Protein Characterization Using Fluorescent Fingerprint Patterns
K. Usui, T. Ojima, M. Takahashi, K. Nokihara, H. Mihara
Biopolymers, 76, 129-139.
Peptide arrays with designed α-helical structures for characterization of proteins from FRET-fingerprint patterns
K. Usui, M. Takahashi, K. Nokihara, H. Mihara
Mol. Div., 8, 209-218.
Fabrication of Nanofibers with Uniform Morphology by Self-Assembly of Designed Peptides
S. Matsumura, S. Uemura, H. Mihara
Chem. Eur. J., 10, 2789-2794.
De Novo Design of Peptides with L-α-Nucleobase Amino Acids and Their Binding Properties to the P22 boxB RNA and its Mutants
H. Miyanishi, T. Takahashi, H. Mihara
Bioconjugate Chem., 15, 694-698.
Construction of a Protein Array on Amyloid-like Fibrils using Coassembly
of Designed Peptides
H. Kodama,S. Matsumura,T. Yamashita, H. Mihara
Chem. Commun., 2876-2877.
Construction of the Novel Conformationally-Restricted Peptide
Library for Screening of Peptides that Control the Interaction Between
Nucleobases
M. Takahashi, A. Ueno, H. Mihara
Bioorg. Med. Chem. Lett., 12, 955-958.
Nucleobase amino acids incorporated into the HIV-1 nucleocapsid
protein increased the binding affinity and specificity for a hairpin
RNA
T. Takahashi, A. Ueno, H. Mihara
ChemBioChem, 3, 543-549.
Molecule-Responsive Fluorescent Sensors of α-Helix Peptides Bearing α-Cyclodextrin,
Pyrene and Nitrobenzene Units in Their Side Chains
M. A. Hossain, K. Takahashi, H. Mihara, A. Ueno
J. Inclusion Phenom. Macrocycl. Chem., 43, 271-277.
Supramolecular Chemistry of Cyclodextrin-Peptides:
Azobenzene-Tagged Prptide
A. Ueno, T. Shimizu, H. Mihara, K. Hamasaki, K. Pitchumani
J. Inclusion Phenom. Macrocycl. Chem., 44, 49-52.
Synthesis and Atomic Force Microscopy Observations of the Single Peptide
Nanotubes and their Micro-order Assemblies
T. Nakanishi, H. Okamoto, Y. Nagai, K. Takeda, I. Obataya, H. Mihara, H.
Azehara, W. Mizutani, K. Furukawa, K. Torimitsu
Bioconjugate Chem., 15, 694-698.
ペプチドアレイを用いたプロテインチップの実用化を目指した研究
軒原清史、大山貴文、臼井健二、米村耕一、富崎欣也、三原久和
高分子論文集、61, 523-532.
Theoretical Prediction and AFM Observations of the Protein Nanotube Consisting of Homo-L-Amino Acid Penta-Peptide Nanorings
H. Okamoto, T. Nakanishi, Y. Nagai, K.Takeda, I. Obataya, H. Mihara, H. Azehara, W. Mizutani
Jpn. J. Appl. Plhys., 42, 676-679.
Construction of a Protein-Detection System Using a Loop Peptide Library
with a Fluorescence Label
M. Takahashi, K. Nokihara, H. Mihara
Chem. Biol., 10, 53-60.
Sensing Behavior of Fluorescent Cyclodextrin/Peptide Hybrids
Bearing a Macrocyclic Metal Complex
S. Furukawa, H. Mihara, A. Ueno
Macromol. Rapid Commun., 24, 202-206.
Novel Peptides Bearing Pyrene and Coumarin Units with or without β-Cyclodextrin
in Their Side Chains Exhibit Intramolecular Fluorescence Resonance Energy
Transfer
M. A. Hossain, H. Mihara, A. Ueno
J. Am. Chem. Soc., 125, 11178-11179.
Complementary Nucleobase Interaction Enhances Peptide-Peptide
Recognition and Self-Replicating Catalysis
S. Matsumura, T. Takahashi, A. Ueno, H. Mihara
Chem. Eur. J., 9, 4829-4837.
Inhibition of Peptide Amyloid Formation by Cationic Peptides
with Homologous Sequences
T. Yamashita, Y. Takahashi, T. Takahashi, H. Mihara
Bioorg. Med. Chem. Lett., 13, 4051-4054.
Fluorescence Resonance Energy Transfer in a Novel
Cyclodextrin-Peptide Conjugate for Detecting Steroid Molecules
M. A. Hossain, H. Mihara, A. Ueno
Bioorg. Med. Chem. Lett., 13, 4305-4308.
Double Naphthalene-Tagged Cyclodextrin-Peptide Capable of Exhibiting Guest-Induced Naphthalene Excimer Fluorescence
D. Yana, T. Shimizu, K. Hamasaki, H. Mihara, A. Ueno
Macromol.
Rapid Commun., 23, 11-15.
Amyloid Architecture: Complementary Assembly of Heterogeneous Combinations
of Three or Four Peptides into Amyloid Fibrils
Y. Takahashi, A. Ueno, H. Mihara
ChemBioChem, 3, 637-642.
Fluorescent Cyclodextrin/Peptide Hybrids with a Novel Guest-Responsive
Chemosensor in the Peptide Side Chain
T. Toyoda, H. Mihara, A. Ueno
Macromol. Rapid Commun., 23, 905-908.
Construction of the Novel Conformationally-Restricted Peptide Library for
Screening of Peptides that Control the Interaction Between Nucleobases
M. Takahashi, A. Ueno, H. Mihara
Bioorg. Med. Chem. Lett., 12, 955-958.
Nucleobase Amino Acids Incorporated into the HIV-1 Nucleocapsid Protein
Increased the Binding Affinity and Specificity for a Hairpin RNA
T. Takahashi, A. Ueno, H. Mihara
ChemBioChem, 3, 543-549.
"Selected as cover"
Molecule-Responsive Fluorescent Sensors of α-Helix Peptides
Bearing α-Cyclodextrin, Pyrene and Nitrobenzene Units in Their Side
Chains
M. A. Hossain, K. Takahashi, H. Mihara, A. Ueno
J. Inclusion Phenom. Macrocycl. Chem., 43, 271-277.
Supramolecular Chemistry of Cyclodextrin-Peptides: Azobenzene-Tagged Prptide
A. Ueno, T. Shimizu, H. Mihara, K. Hamasaki, K. Pitchumani
J. Inclusion Phenom. Macrocycl. Chem., 44, 49-52.
Synthesis and Atomic Force Microscopy Observations of the Single
Peptide Nanotubes and their Micro-order Assemblies
T. Nakanishi, H. Okamoto, Y. Nagai, K. Takeda, I. Obataya, H. Mihara, H.
Azehara, W. Mizutani, K. Furukawa, K. Torimitsu
Phys. Rev. B, 66, 165417-1-8.
Guest-Induced Diminishment in Fluorescence Quenching and Molecule Sensing Ability of a Novel Cyclodextrin-Peptide Conjugate
M. A. Hossain, K. Hamasaki, K. Takahashi, H. Mihara, A. Ueno
J. Am. Chem. Soc., 123, 7435-7436.
Remarkable Stabilization of the α-Helix Structure by an Intramolecular
Host-Guest Bridge in a Cyclodextrin-Peptide Hybrid
K. Hamasaki, R. Suzuki, H. Mihara, A. Ueno
Macromol. Rapid Commun., 22, 262-265
Construction of Peptide Conjugates with Peptide Nucleic Acids Containing
an Anthracene Probe and Their Interactions with DNA
G. Balasundarm, T. Takahashi, K. Hamasaki, A. Ueno, H. Mihara
Bioorg. Med. Chem., 9, 1115-1121.
Construction of Peptides with Nucleobase Amino Acids: Design and Synthesis of the Nucleobase-Conjugated Peptides Derived from HIV-1 Rev and Their Binding Properties to HIV-1 RRE RNA
T. Takahashi, K. Hamasaki, A. Ueno, H. Mihara
Bioorg. Med. Chem., 9, 991-1000.
HIV Rev Peptides Conjugated with Peptide Nucleic Acids and Their Efficient
Binding to RRE RNA
I. Kumagai, T. Takahashi, K. Hamasaki, A. Ueno, H. Mihara
Bioorg. Med. Chem. Lett., 11, 1169-1172.
Photoinduced Hydrogen Evolution with Peptide Dendrimer Multi-Zn(II)-Porphyrin,
Viologen and Hydrogenase
M. Sakamoto, T. Kamachi, I. Okura, A. Ueno, H. Mihara
Biopolymers, 59, 103-119.
Design and Synthesis of 3α-Helix Peptides Forming a Cavity for a Fluorescent
Ligand
I. Obataya, S. Sakamoto, A. Ueno, H. Mihara
Biopolymers, 59, 65-71.
Peptide Design Based on an Antibody Complementarity-Determining Region
(CDR): Construction of Porphyrin-Binding Peptides and Their Affinity Maturation
by a Combinatorial Method
M. Takahashi, A. Ueno, H. Mihara
Chem. Eur. J., 6, 3196-3203.
Multi-Peptide-Metalloporphyrin Assembly on a Dendrimer Template and Photoinduced
Electron Transfer Based on the Dendrimer Structure
M. Sakamoto, A. Ueno, H. Mihara
Chem. Eur. J., 7, 2449-2458.
Heterogeneous Assembly of Complementary Peptide Pairs into Amyloid Fibrils
with Structural Transition from α-Helix to β-Sheet
Y. Takahashi, A. Ueno, H. Mihara
ChemBioChem, 2, 75-79.
Self-Assembly of Polypeptides into Amyloid Fibrils with Structural Transitions
H. Mihara, Y. Takahashi
Trans. Material Res. Soc. Jap., 26, 473-478.
Cyclodextrin-Peptide Hybrid as a Hydrolytic Catalyst Having
Multiple Functional Groups
H. Tsutsumi, K. Hamasaki, H. Mihara, A. Ueno
Bioorg. Med. Chem. Lett., 10, 0741-744.
A High-Throughput Screening Utilizing Intramolecular
Fluorescence Resonance Energy Transfer for the Discovery of the Molecules That
Bind HIV-1 TAR RNA Specifically
C. Matsumoto, K. Hamasaki, H. Mihara, A. Ueno
Bioorg. Med. Chem. Lett., 10, 1857-1861.
Association and Guest-Induced Dissociation of a Novel α-Helix Peptide Bearing
Pyrene and γ-Cyclodextrin in the Side Chain
M. A. Hossain, K. Hamasaki, H. Mihara, A. Ueno
Chem. Lett., 252-253.
Association of α-Helix Peptides That Have γ-Cyclodextrin in the Side Chain,
and Induction of Dissociation of the Association Dimer by External Stimulant
Molecules
M. A. Hossain, T. Kanai, S. Matsumura, K. Hamasaki, H. Mihara, A. Ueno
J. Chem. Soc. Perkin Trans. 2, 1527-1533.
Rate Enhancement and Enantioselectivity in Ester Hydrolysis Catalysed by
Cyclodextrin-Peptide Hybrids
H. Tsutsumi, K. Hamasaki, H. Mihara, A. Ueno
J. Chem. Soc. Perkin Trans 2, 1813-1818.
Guest-Responsive Excimer Emission in an α-Helix Peptide Bearing
γ-Cyclodextrin and Two Naphthalene Units
T. Toyoda, S. Matsumura, H. Mihara, A. Ueno
Macromol. Rapid. Commun., 21, 485-488.
Construction of Two-Stranded α-Helix Peptides Based on Influenza
Virus M1 Protein Selectively Bound to RNA
H. Kumagai, T. Takahashi, K. Nagata, A. Ueno, H. Mihara
Bioorg. Med. Chem. Lett., 10, 2227-2230.
Construction of HIV Rev Peptides Containing Peptide Nucleic Acid That Bind
HIV RRE IIB RNA
I. Kumagai, T.Takahashi, H. Mihara, A. Ueno
Bioorg. Med. Chem. Lett., 10, 377-380.
Design, Synthesis and Peroxidase-like Activity of 3α-Helix
Proteins Covalently Bound to Heme
I. Obataya, T. Kotaki, S. Sakamoto, A. Ueno, H. Mihara
Bioorg. Med. Chem. Lett., 10, 2719-2722.
Design of a Nucleobase-Conjugated Peptide That Recognizes HIV-1
RRE IIB RNA with High Affinity and Specificity
T. Takahashi, K. Hamasaki, I. Kumagai, A. Ueno, H. Mihara
Chem. Commun., 349-350.
Peptides with Nucleobase Moieties as a Stabilizing Factor for a Two-Stranded
α-Helix
S. Matsumura, A. Ueno, H. Mihara
Chem. Commun., 1615-1616.
Construction of α-Helical Peptide Dendrimers Conjugated with
Multi-Metalloporphyrins: Photoinduced Electron Transfer on Dendrimer
Architecture
M. Sakamoto, A. Ueno, H. Mihara
Chem. Commun., 1741-1742.
Construction of α-Helix Peptides with β-Cyclodextrin and Dansyl
Units and Their Conformational and Molecular Sensing Properties
S. Matsumura, S. Sakamoto, A. Ueno, H. Mihara
Chem. Eur. J., 6, 1781-1788.
Peptide Design Based on an Antibody CDR: Construction of
Porphyrin-Binding Peptides and Their Affinity Maturation by a Combinatorial
Method
M. Takahashi, A. Ueno, H. Mihara
Chem. Eur. J., 6, 3196-3203.
Design and Characterization of Flavoemzyme Models in the Course
of Chemical Evolution of Four-α-Helix Bundle Polypeptides
K.-Y. Tomizaki, Y. Tsunekawa, H. Akisada, H. Mihara, N. Nishino
J. Chem. Soc., Perkin Trans. 2, 813-822
Mutational Analysis of Designed Peptides that Undergo Structural
Transition from α-Helix to β-Sheet and Amyloid Fibril Formation
Y. Takahashi, A. Ueno, H. Mihara
Structure, 8, 915-925.
Construction of Peptides that Undergo Structural Transition from
α-Helix to β-Sheet and Amyloid Fibril Formation by the Introduction of
N-Terminal Hydrophobic Amino Acids
Y. Takahashi, T. Yamashita, A. Ueno, H. Mihara
Tetrahedron, 56, 7011-7018.
Sorry, underconstruction...
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